Patient-centered psycho-oncology is a holistic approach to the care of cancer patients that pays attention to the psychological, social, and emotional dimensions of the disease in addition to their physical condition . In this approach, the patient is not only the recipient of the treatment services, but is also recognized as an active member of the treatment process, and his values, needs, concerns, and preferences are important in treatment decisions. Joint decision-making between the patient and the oncology team Cancer can increase a person's sense of threat, uncertainty, anxiety, and reduced control over life, thereby undermining their belief in their ability to manage the disease. In such a situation, the patient's participation in treatment decisions can increase a sense of agency and Strengthen their psychological independence . Self-efficacy refers to a person's belief about their ability to cope with the disease, manage symptoms, follow treatment, and adapt to life changes, and is considered one of the important factors in the psychological adjustment of cancer patients. When the patient receives enough and understandable information and has the opportunity to express his concerns and preferences, he or she is more likely to experience himself as a capable person in managing the condition of the disease. Shared decision-making can also increase a sense of control as the patient feels heard along the way to treatment, their choices are respected, and they have an active role in their future. In this process, the psycho-oncologist can provide the basis for more effective patient participation by identifying anxiety, fear, psychological distress, negative thoughts, and communication barriers. This approach can be used at different stages of cancer, from diagnosis and treatment selection to pain and symptom control, complications management, supportive care, and adjustment to life after treatment. However, patients differ in the degree of willingness to participate, intense anxiety, fatigue, complexity of medical information, Low health literacy and time constraints are among the most important challenges in implementing joint decision-making. Cultural and family differences can also affect the degree of autonomy of the patient and the way he or she participates in treatment decisions. Also, in some patients, the severity of the illness or cognitive and emotional problems may reduce the ability to participate effectively. Therefore, shared decision-making should not mean transferring responsibility for difficult decisions to the patient, but rather should be a supportive process tailored to his/her psychological capacity and preferences. To reinforce this approach, it is essential to regularly assess self-efficacy, sense of control, and psychological distress, teach communication skills to the oncology team, provide information in plain language, and provide ample opportunities for dialogue. The active presence of a psycho-oncologist in the treatment team can also help identify psychological barriers and increase the patient's readiness to participate. Overall, the integration of patient-centered psycho-oncology with shared decision-making can transform the patient from a passive recipient of services to an active partner in the treatment process. This approach can help to better adapt to the disease, participate more effectively in treatment, and improve the quality of life of cancer patients by enhancing self-efficacy, increasing the sense of control, and reducing psychological helplessness.